PD 174265( PD174265 | PD-174265 | N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide )

Catalog No. M27910 CAS No. 216163-53-0

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

PD 174265
Note

Research use only, not for human use.
Brief Description

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
Description

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
In Vitro

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In Vivo

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Synonyms

PD174265 | PD-174265 | N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide
Pathway

Angiogenesis
Target

EGFR
Recptor

Influenza Virus
Research Area

——
Indication

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Chemical Information

CAS Number

216163-53-0
Formula Weight

371.238
Molecular Formula

C17H15BrN4O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (336.72 mM)
SMILES

CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Takizawa N, et al. Anti-influenza virus activity of a salcomine derivative mediated by inhibition of viral RNA synthesis. Arch Virol. 2018 Jun;163(6):1607-1614.

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